[{"id":1,"result":"amenable","nucleotide_change_value_index":"c.[11G\u003eT; 620A\u003eC]","nucleotide_change_simple_value_index":"c.G11T/A620C","protein_sequence_change_value_index":"R4M/Y207S","no_confirmed_link_to_fabry":false,"not_all_patients_with_confirmed_fabry":false,"multimutations":[{"nucleotide_change":"c.11G\u003eT","protein_sequence_change":"R4M","nucleotide_change_simple":"c.G11T","protein_sequence_change_long":"p.(Arg4Met)"},{"nucleotide_change":"c.620A\u003eC","protein_sequence_change":"Y207S","nucleotide_change_simple":"c.A620C","protein_sequence_change_long":"p.(Tyr207Ser)"}]},{"id":2,"result":"amenable","nucleotide_change_value_index":"c.[157A\u003eC; 158A\u003eT]","nucleotide_change_simple_value_index":"c.A157C/A158T","protein_sequence_change_value_index":"N53L","no_confirmed_link_to_fabry":null,"not_all_patients_with_confirmed_fabry":null,"multimutations":[{"nucleotide_change":"c.157A\u003eC","protein_sequence_change":"N53L","nucleotide_change_simple":"c.A157C","protein_sequence_change_long":"p.(Asn53Leu)"},{"nucleotide_change":"c.158A\u003eT","protein_sequence_change":"N53L","nucleotide_change_simple":"c.A158T","protein_sequence_change_long":"p.(Asn53Leu)"}]},{"id":3,"result":"amenable","nucleotide_change_value_index":"c.[164A\u003eT; 170A\u003eT]","nucleotide_change_simple_value_index":"c.A164T/A170T","protein_sequence_change_value_index":"D55V/Q57L","no_confirmed_link_to_fabry":null,"not_all_patients_with_confirmed_fabry":null,"multimutations":[{"nucleotide_change":"c.164A\u003eT","protein_sequence_change":"D55V","nucleotide_change_simple":"c.A164T","protein_sequence_change_long":"p.(Asp55Val)"},{"nucleotide_change":"c.170A\u003eT","protein_sequence_change":"Q57L","nucleotide_change_simple":"c.A170T","protein_sequence_change_long":"p.(Gln57Leu)"}]},{"id":4,"result":"amenable","nucleotide_change_value_index":"c.[253G\u003eA; 254G\u003eA]","nucleotide_change_simple_value_index":"c.G253A/G254A","protein_sequence_change_value_index":"G85N","no_confirmed_link_to_fabry":false,"not_all_patients_with_confirmed_fabry":false,"multimutations":[{"nucleotide_change":"c.253G\u003eA","protein_sequence_change":"G85N","nucleotide_change_simple":"c.G253A","protein_sequence_change_long":"p.(Gly85Asn)"},{"nucleotide_change":"c.254G\u003eA","protein_sequence_change":"G85N","nucleotide_change_simple":"c.G254A","protein_sequence_change_long":"p.(Gly85Asn)"}]},{"id":5,"result":"amenable","nucleotide_change_value_index":"c.[253G\u003eA; 254G\u003eT; 255T\u003eG]","nucleotide_change_simple_value_index":"c.G253A/G254T/T255G","protein_sequence_change_value_index":"G85M","no_confirmed_link_to_fabry":null,"not_all_patients_with_confirmed_fabry":null,"multimutations":[{"nucleotide_change":"c.253G\u003eA","protein_sequence_change":"G85M","nucleotide_change_simple":"c.G253A","protein_sequence_change_long":"p.(Gly85Met)"},{"nucleotide_change":"c.254G\u003eT","protein_sequence_change":"G85M","nucleotide_change_simple":"c.G254T","protein_sequence_change_long":"p.(Gly85Met)"},{"nucleotide_change":"c.255T\u003eG","protein_sequence_change":"G85M","nucleotide_change_simple":"c.T255G","protein_sequence_change_long":"p.(Gly85Met)"}]},{"id":6,"result":"amenable","nucleotide_change_value_index":"c.[496C\u003eG; 497T\u003eG]","nucleotide_change_simple_value_index":"c.C496G/T497G","protein_sequence_change_value_index":"L166G","no_confirmed_link_to_fabry":null,"not_all_patients_with_confirmed_fabry":null,"multimutations":[{"nucleotide_change":"c.496C\u003eG","protein_sequence_change":"L166G","nucleotide_change_simple":"c.C496G","protein_sequence_change_long":"p.(Leu166Gly)"},{"nucleotide_change":"c.497T\u003eG","protein_sequence_change":"L166G","nucleotide_change_simple":"c.T497G","protein_sequence_change_long":"p.(Leu166Gly)"}]},{"id":7,"result":"amenable","nucleotide_change_value_index":"c.[644A\u003eG; 937G\u003eT]","nucleotide_change_simple_value_index":"c.A644G/G937T","protein_sequence_change_value_index":"N215S/D313Y","no_confirmed_link_to_fabry":null,"not_all_patients_with_confirmed_fabry":true,"multimutations":[{"nucleotide_change":"c.644A\u003eG","protein_sequence_change":"N215S","nucleotide_change_simple":"c.A644G","protein_sequence_change_long":"p.(Asn215Ser)"},{"nucleotide_change":"c.937G\u003eT","protein_sequence_change":"D313Y","nucleotide_change_simple":"c.G937T","protein_sequence_change_long":"p.(Asp313Tyr)"}]},{"id":8,"result":"amenable","nucleotide_change_value_index":"c.[811G\u003eA; 937G\u003eT]","nucleotide_change_simple_value_index":"c.G811A/G937T","protein_sequence_change_value_index":"G271S/D313Y","no_confirmed_link_to_fabry":null,"not_all_patients_with_confirmed_fabry":true,"multimutations":[{"nucleotide_change":"c.811G\u003eA","protein_sequence_change":"G271S","nucleotide_change_simple":"c.G811A","protein_sequence_change_long":"p.(Gly271Ser)"},{"nucleotide_change":"c.937G\u003eT","protein_sequence_change":"D313Y","nucleotide_change_simple":"c.G937T","protein_sequence_change_long":"p.(Asp313Tyr)"}]},{"id":9,"result":"amenable","nucleotide_change_value_index":"c.[937G\u003eT; 1232G\u003eA]","nucleotide_change_simple_value_index":"c.G937T/G1232A","protein_sequence_change_value_index":"D313Y/G411D","no_confirmed_link_to_fabry":false,"not_all_patients_with_confirmed_fabry":true,"multimutations":[{"nucleotide_change":"c.937G\u003eT","protein_sequence_change":"D313Y","nucleotide_change_simple":"c.G937T","protein_sequence_change_long":"p.(Asp313Tyr)"},{"nucleotide_change":"c.1232G\u003eA","protein_sequence_change":"G411D","nucleotide_change_simple":"c.G1232A","protein_sequence_change_long":"p.(Gly411Asp)"}]},{"id":10,"result":"nonamenable","nucleotide_change_value_index":"c.[138C\u003eG; 153G\u003eT; 167G\u003eT]","nucleotide_change_simple_value_index":"c.C138G/G153T/G167T","protein_sequence_change_value_index":"H46Q/M51I/C56F","no_confirmed_link_to_fabry":null,"not_all_patients_with_confirmed_fabry":null,"multimutations":[{"nucleotide_change":"c.138C\u003eG","protein_sequence_change":"H46Q","nucleotide_change_simple":"c.C138G","protein_sequence_change_long":"p.(His46Gln)"},{"nucleotide_change":"c.153G\u003eT","protein_sequence_change":"M51I","nucleotide_change_simple":"c.G153T","protein_sequence_change_long":"p.(Met51Ile)"},{"nucleotide_change":"c.167G\u003eT","protein_sequence_change":"C56F","nucleotide_change_simple":"c.G167T","protein_sequence_change_long":"p.(Cys56Phe)"}]},{"id":11,"result":"nonamenable","nucleotide_change_value_index":"c.[196G\u003eC; 1061T\u003eA]","nucleotide_change_simple_value_index":"c.G196C/T1061A","protein_sequence_change_value_index":"E66Q/I354K","no_confirmed_link_to_fabry":null,"not_all_patients_with_confirmed_fabry":null,"multimutations":[{"nucleotide_change":"c.196G\u003eC","protein_sequence_change":"E66Q","nucleotide_change_simple":"c.G196C","protein_sequence_change_long":"p.(Glu66Gln)"},{"nucleotide_change":"c.1061T\u003eA","protein_sequence_change":"I354K","nucleotide_change_simple":"c.T1061A","protein_sequence_change_long":"p.(Ile354Lys)"}]},{"id":12,"result":"nonamenable","nucleotide_change_value_index":"c.[280T\u003eA; 281G\u003eC]","nucleotide_change_simple_value_index":"c.T280A/G281C","protein_sequence_change_value_index":"C94T","no_confirmed_link_to_fabry":null,"not_all_patients_with_confirmed_fabry":null,"multimutations":[{"nucleotide_change":"c.280T\u003eA","protein_sequence_change":"C94T","nucleotide_change_simple":"c.T280A","protein_sequence_change_long":"p.(Cys94Thr)"},{"nucleotide_change":"c.281G\u003eC","protein_sequence_change":"C94T","nucleotide_change_simple":"c.G281C","protein_sequence_change_long":"p.(Cys94Thr)"}]},{"id":13,"result":"nonamenable","nucleotide_change_value_index":"c.[358C\u003eT; 359T\u003eC]","nucleotide_change_simple_value_index":"c.C358T/T359C","protein_sequence_change_value_index":"L120S","no_confirmed_link_to_fabry":null,"not_all_patients_with_confirmed_fabry":null,"multimutations":[{"nucleotide_change":"c.358C\u003eT","protein_sequence_change":"L120S","nucleotide_change_simple":"c.C358T","protein_sequence_change_long":"p.(Leu120Ser)"},{"nucleotide_change":"c.359T\u003eC","protein_sequence_change":"L120S","nucleotide_change_simple":"c.T359C","protein_sequence_change_long":"p.(Leu120Ser)"}]},{"id":14,"result":"nonamenable","nucleotide_change_value_index":"c.[359T\u003eC; 361G\u003eA]","nucleotide_change_simple_value_index":"c.T359C/G361A","protein_sequence_change_value_index":"L120P/A121T","no_confirmed_link_to_fabry":null,"not_all_patients_with_confirmed_fabry":null,"multimutations":[{"nucleotide_change":"c.359T\u003eC","protein_sequence_change":"L120P","nucleotide_change_simple":"c.T359C","protein_sequence_change_long":"p.(Leu120Pro)"},{"nucleotide_change":"c.361G\u003eA","protein_sequence_change":"A121T","nucleotide_change_simple":"c.G361A","protein_sequence_change_long":"p.(Ala121Thr)"}]},{"id":15,"result":"nonamenable","nucleotide_change_value_index":"c.[644A\u003eG; 811G\u003eA]","nucleotide_change_simple_value_index":"c.A644G/G811A","protein_sequence_change_value_index":"N215S/G271S","no_confirmed_link_to_fabry":null,"not_all_patients_with_confirmed_fabry":null,"multimutations":[{"nucleotide_change":"c.644A\u003eG","protein_sequence_change":"N215S","nucleotide_change_simple":"c.A644G","protein_sequence_change_long":"p.(Asn215Ser)"},{"nucleotide_change":"c.811G\u003eA","protein_sequence_change":"G271S","nucleotide_change_simple":"c.G811A","protein_sequence_change_long":"p.(Gly271Ser)"}]},{"id":16,"result":"nonamenable","nucleotide_change_value_index":"c.[644A\u003eG; 811G\u003eA; 937G\u003eT]","nucleotide_change_simple_value_index":"c.A644G/G811A/G937T","protein_sequence_change_value_index":"N215S/G271S/D313Y","no_confirmed_link_to_fabry":null,"not_all_patients_with_confirmed_fabry":null,"multimutations":[{"nucleotide_change":"c.644A\u003eG","protein_sequence_change":"N215S","nucleotide_change_simple":"c.A644G","protein_sequence_change_long":"p.(Asn215Ser)"},{"nucleotide_change":"c.811G\u003eA","protein_sequence_change":"G271S","nucleotide_change_simple":"c.G811A","protein_sequence_change_long":"p.(Gly271Ser)"},{"nucleotide_change":"c.937G\u003eT","protein_sequence_change":"D313Y","nucleotide_change_simple":"c.G937T","protein_sequence_change_long":"p.(Asp313Tyr)"}]},{"id":17,"result":"nonamenable","nucleotide_change_value_index":"c.[790G\u003eT; 805G\u003eA]","nucleotide_change_simple_value_index":"c.G790T/G805A","protein_sequence_change_value_index":"D264Y/V269M","no_confirmed_link_to_fabry":null,"not_all_patients_with_confirmed_fabry":null,"multimutations":[{"nucleotide_change":"c.790G\u003eT","protein_sequence_change":"D264Y","nucleotide_change_simple":"c.G790T","protein_sequence_change_long":"p.(Asp264Tyr)"},{"nucleotide_change":"c.805G\u003eA","protein_sequence_change":"V269M","nucleotide_change_simple":"c.G805A","protein_sequence_change_long":"p.(Val269Met)"}]},{"id":18,"result":"nonamenable","nucleotide_change_value_index":"c.[806T\u003eG; 937G\u003eT]","nucleotide_change_simple_value_index":"c.T806G/G937T","protein_sequence_change_value_index":"V269G/D313Y","no_confirmed_link_to_fabry":null,"not_all_patients_with_confirmed_fabry":null,"multimutations":[{"nucleotide_change":"c.806T\u003eG","protein_sequence_change":"V269G","nucleotide_change_simple":"c.T806G","protein_sequence_change_long":"p.(Val269Gly)"},{"nucleotide_change":"c.937G\u003eT","protein_sequence_change":"D313Y","nucleotide_change_simple":"c.G937T","protein_sequence_change_long":"p.(Asp313Tyr)"}]},{"id":19,"result":"nonamenable","nucleotide_change_value_index":"c.[374A\u003eT; 383G\u003eA]","nucleotide_change_simple_value_index":"c.A374T/G383A","protein_sequence_change_value_index":"H125L/G128E","no_confirmed_link_to_fabry":null,"not_all_patients_with_confirmed_fabry":null,"multimutations":[{"nucleotide_change":"c.374A\u003eT","protein_sequence_change":"H125L","nucleotide_change_simple":"c.A374T","protein_sequence_change_long":"p.(His125Leu)"},{"nucleotide_change":"c.383G\u003eA","protein_sequence_change":"G128E","nucleotide_change_simple":"c.G383A","protein_sequence_change_long":"p.(Gly128Glu)"}]},{"id":20,"result":"nonamenable","nucleotide_change_value_index":"c.[604T\u003eC; 644A\u003eG]","nucleotide_change_simple_value_index":"c.T604C/A644G","protein_sequence_change_value_index":"C202R/N215S","no_confirmed_link_to_fabry":false,"not_all_patients_with_confirmed_fabry":false,"multimutations":[{"nucleotide_change":"c.604T\u003eC","protein_sequence_change":"C202R","nucleotide_change_simple":"c.T604C","protein_sequence_change_long":"p.(Cys202Arg)"},{"nucleotide_change":"c.644A\u003eG","protein_sequence_change":"N215S","nucleotide_change_simple":"c.A644G","protein_sequence_change_long":"p.(Asn215Ser)"}]},{"id":21,"result":"nonamenable","nucleotide_change_value_index":"g.[10237_11932del; 11933_12083inv; 12084_12097del]","nucleotide_change_simple_value_index":"g.10237_11932del/11933_12083inv/12084_12097del","protein_sequence_change_value_index":"UNKNOWN","no_confirmed_link_to_fabry":null,"not_all_patients_with_confirmed_fabry":null,"multimutations":[{"nucleotide_change":"g.10237_11932del","protein_sequence_change":null,"nucleotide_change_simple":"g.10237_11932del","protein_sequence_change_long":null},{"nucleotide_change":"g.11933_12083inv","protein_sequence_change":null,"nucleotide_change_simple":"g.11933_12083inv","protein_sequence_change_long":null},{"nucleotide_change":"g.12084_12097del","protein_sequence_change":null,"nucleotide_change_simple":"g.12084_12097del","protein_sequence_change_long":null}]},{"id":22,"result":"nonamenable","nucleotide_change_value_index":"IVS6-10G\u003eA; IVS6-22C\u003eT","nucleotide_change_simple_value_index":"c.1000-10G\u003eA/1000-22C\u003eT","protein_sequence_change_value_index":"UNKNOWN","no_confirmed_link_to_fabry":null,"not_all_patients_with_confirmed_fabry":null,"multimutations":[{"nucleotide_change":"IVS6-10G\u003eA","protein_sequence_change":null,"nucleotide_change_simple":"c.1000-10G\u003eA","protein_sequence_change_long":null},{"nucleotide_change":"IVS6-22C\u003eT","protein_sequence_change":null,"nucleotide_change_simple":"c.1000-22C\u003eT","protein_sequence_change_long":null}]},{"id":23,"result":"nonamenable","nucleotide_change_value_index":"IVS1-2A\u003eG; IVS1-49T\u003eC","nucleotide_change_simple_value_index":"c.195-2A\u003eG/195-49T\u003eC","protein_sequence_change_value_index":"UNKNOWN","no_confirmed_link_to_fabry":null,"not_all_patients_with_confirmed_fabry":null,"multimutations":[{"nucleotide_change":"IVS1-2A\u003eG","protein_sequence_change":null,"nucleotide_change_simple":"c.195-2A\u003eG","protein_sequence_change_long":null},{"nucleotide_change":"IVS1-49T\u003eC","protein_sequence_change":null,"nucleotide_change_simple":"c.195-49T\u003eC","protein_sequence_change_long":null}]},{"id":24,"result":"nonamenable","nucleotide_change_value_index":"c.[1067G\u003eA; 1078G\u003eC]","nucleotide_change_simple_value_index":"c.G1067A/G1078C","protein_sequence_change_value_index":"R356Q/G360R","no_confirmed_link_to_fabry":false,"not_all_patients_with_confirmed_fabry":false,"multimutations":[{"nucleotide_change":"c.1067G\u003eA","protein_sequence_change":"R356Q","nucleotide_change_simple":"c.G1067A","protein_sequence_change_long":"p.(Arg356Gln)"},{"nucleotide_change":"c.1078G\u003eC","protein_sequence_change":"G360R","nucleotide_change_simple":"c.G1078C","protein_sequence_change_long":"p.(Gly360Arg)"}]},{"id":25,"result":"nonamenable","nucleotide_change_value_index":"c.[196G\u003eC; 334C\u003eT]","nucleotide_change_simple_value_index":"c.G196C/C334T","protein_sequence_change_value_index":"E66Q/R112C","no_confirmed_link_to_fabry":false,"not_all_patients_with_confirmed_fabry":false,"multimutations":[{"nucleotide_change":"c.196G\u003eC","protein_sequence_change":"E66Q","nucleotide_change_simple":"c.G196C","protein_sequence_change_long":"p.(Glu66Gln)"},{"nucleotide_change":"c.334C\u003eT","protein_sequence_change":"R112C","nucleotide_change_simple":"c.C334T","protein_sequence_change_long":"p.(Arg112Cys)"}]},{"id":26,"result":"nonamenable","nucleotide_change_value_index":"c.[836A\u003eT; 902G\u003eA]","nucleotide_change_simple_value_index":"c.A836T/G902A","protein_sequence_change_value_index":"Q279L/R301Q","no_confirmed_link_to_fabry":false,"not_all_patients_with_confirmed_fabry":false,"multimutations":[{"nucleotide_change":"c.836A\u003eT","protein_sequence_change":"Q279L","nucleotide_change_simple":"c.A836T","protein_sequence_change_long":"p.(Gln279Leu)"},{"nucleotide_change":"c.902G\u003eA","protein_sequence_change":"R301Q","nucleotide_change_simple":"c.G902A","protein_sequence_change_long":"p.(Arg301Gln)"}]},{"id":27,"result":"amenable","nucleotide_change_value_index":"c.[399T\u003eG; 434T\u003eC]","nucleotide_change_simple_value_index":"c.T399G/T434C","protein_sequence_change_value_index":"I133M/F145S","no_confirmed_link_to_fabry":false,"not_all_patients_with_confirmed_fabry":false,"multimutations":[{"nucleotide_change":"c.399T\u003eG","protein_sequence_change":"I133M","nucleotide_change_simple":"c.T399G","protein_sequence_change_long":"p.(Ile133Met)"},{"nucleotide_change":"c.434T\u003eC","protein_sequence_change":"F145S","nucleotide_change_simple":"c.T434C","protein_sequence_change_long":"p.(Phe145Ser)"}]},{"id":28,"result":"amenable","nucleotide_change_value_index":"c.[70T\u003eA; 1255A\u003eG]","nucleotide_change_simple_value_index":"c.T70A/A1255G","protein_sequence_change_value_index":"W24R/N419D","no_confirmed_link_to_fabry":false,"not_all_patients_with_confirmed_fabry":false,"multimutations":[{"nucleotide_change":"c.1255A\u003eG","protein_sequence_change":"N419D","nucleotide_change_simple":"c.A1255G","protein_sequence_change_long":"p.(Asn419Asp)"},{"nucleotide_change":"c.70T\u003eA","protein_sequence_change":"W24R","nucleotide_change_simple":"c.T70A","protein_sequence_change_long":"p.(Trp24Arg)"}]},{"id":29,"result":"amenable","nucleotide_change_value_index":"c.[218C\u003eT; 525C\u003eG]","nucleotide_change_simple_value_index":"c.C218T/C525G","protein_sequence_change_value_index":"A73V/D175E","no_confirmed_link_to_fabry":false,"not_all_patients_with_confirmed_fabry":false,"multimutations":[{"nucleotide_change":"c.218C\u003eT","protein_sequence_change":"A73V","nucleotide_change_simple":"c.C218T","protein_sequence_change_long":"p.(Ala73Val)"},{"nucleotide_change":"c.525C\u003eG","protein_sequence_change":"D175E","nucleotide_change_simple":"c.C525G","protein_sequence_change_long":"p.(Asp175Glu)"}]},{"id":30,"result":"nonamenable","nucleotide_change_value_index":"c.[335G\u003eA; 937G\u003eT]","nucleotide_change_simple_value_index":"c.G335A/G937T","protein_sequence_change_value_index":"R112H/D313Y","no_confirmed_link_to_fabry":false,"not_all_patients_with_confirmed_fabry":false,"multimutations":[{"nucleotide_change":"c.335G\u003eA","protein_sequence_change":"R112H","nucleotide_change_simple":"c.G335A","protein_sequence_change_long":"p.(Arg112His)"},{"nucleotide_change":"c.937G\u003eT","protein_sequence_change":"D313Y","nucleotide_change_simple":"c.G937T","protein_sequence_change_long":"p.(Asp313Tyr)"}]},{"id":63,"result":"amenable","nucleotide_change_value_index":"c.[602C\u003eT; 937G\u003eT]","nucleotide_change_simple_value_index":"c.C602T/G937T","protein_sequence_change_value_index":"S201F/D313Y","no_confirmed_link_to_fabry":false,"not_all_patients_with_confirmed_fabry":false,"multimutations":[{"nucleotide_change":"c.602C\u003eT","protein_sequence_change":"S201F","nucleotide_change_simple":"c.C602T","protein_sequence_change_long":"p.(Ser201Phe)"},{"nucleotide_change":"c.937G\u003eT","protein_sequence_change":"D313Y","nucleotide_change_simple":"c.G937T","protein_sequence_change_long":"p.(Asp313Tyr)"}]},{"id":64,"result":"amenable","nucleotide_change_value_index":"c.[578G\u003eT; 936G\u003eC]","nucleotide_change_simple_value_index":"c.G578T/G936C","protein_sequence_change_value_index":"R193M/Q312H","no_confirmed_link_to_fabry":false,"not_all_patients_with_confirmed_fabry":false,"multimutations":[{"nucleotide_change":"c.578G\u003eT","protein_sequence_change":"R193M","nucleotide_change_simple":"c.G578T","protein_sequence_change_long":"p.(Arg193Met)"},{"nucleotide_change":"c.936G\u003eC","protein_sequence_change":"Q312H","nucleotide_change_simple":"c.G936C","protein_sequence_change_long":"p.(Gln312His)"}]}]