Search GLA Mutations
You can use this search tool to find out whether a specific GLA mutation has been classified as amenable to treatment with GALAFOLD® according to the approved SmPC.
GALAFOLD® is indicated for long-term treatment of adults and adolescents aged 12 years and older with a confirmed diagnosis of Fabry disease (α-galactosidase A deficiency) and who have an amenable mutation.
Female patients have two GLA genes on two different chromosomes. The patient is considered amenable if the GLA mutations on either chromosome are amenable. Please utilize the appropriate search function to determine if the mutation or mutations on each chromosome are amenable.
Enter either a nucleotide or amino acid change.
For Nucleotide Change
Please use format c.#A>B or c.A#B for nucleotide sequence changes, where 'c.' is optional; # indicates a number; A and B are letters. Examples: c.8T>C or c.T8C
For Amino Acid Change
Please use format p.A#B for protein sequence changes, where 'p.' is optional; # indicates a number; A and B are letters. Example: p.L3P
*Note: This is only for searching multiple mutations on the same chromosome.
For Nucleotide Change
Please use format c.#A>B or c.A#B for nucleotide sequence changes, where 'c.' is optional; # indicates a number; A and B are letters. Examples: c.8T>C or c.T8C
For Amino Acid Change
Please use format p.A#B for protein sequence changes, where 'p.' is optional; # indicates a number; A and B are letters. Example: p.L3P
ENTER UP TO THREE MUTATIONS
See the SmPC for full prescribing information